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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC16A
All Species:
4.24
Human Site:
S2113
Identified Species:
10.37
UniProt:
O15027
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15027
NP_055681.1
2179
233517
S2113
G
S
Q
G
G
E
L
S
R
C
S
S
M
S
S
Chimpanzee
Pan troglodytes
XP_001171528
1350
147545
R1294
S
S
M
S
S
L
S
R
E
V
S
Q
H
F
N
Rhesus Macaque
Macaca mulatta
XP_001117942
1383
150489
L1327
L
A
R
D
R
P
C
L
R
T
A
L
G
T
A
Dog
Lupus familis
XP_849192
2238
239022
P2165
S
S
Q
G
G
E
A
P
S
D
H
A
P
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91XT4
1051
115505
Q995
I
G
G
F
S
G
T
Q
G
V
S
S
E
F
Y
Rat
Rattus norvegicus
Q75N33
1057
116878
P1000
G
I
G
G
F
S
G
P
Q
G
V
S
S
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521275
2601
280417
S2317
G
S
Q
S
G
E
L
S
R
C
S
S
M
S
S
Chicken
Gallus gallus
Q6AW68
929
102937
P873
Q
P
P
A
S
P
S
P
Y
R
N
P
V
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695457
2216
240508
F2152
S
A
T
V
P
Q
M
F
N
P
N
A
A
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096963
2021
220161
K1965
V
P
G
G
P
Q
P
K
L
Q
S
N
M
F
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.8
56.6
68.5
N.A.
22.7
22.8
N.A.
50.6
20.5
N.A.
37.9
N.A.
20.2
N.A.
N.A.
N.A.
Protein Similarity:
100
61.4
58
75.5
N.A.
30.8
31.2
N.A.
60.3
28.3
N.A.
51.9
N.A.
34
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
33.3
N.A.
13.3
20
N.A.
93.3
6.6
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
40
46.6
N.A.
13.3
26.6
N.A.
93.3
20
N.A.
33.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
10
0
0
10
0
0
0
10
20
10
10
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
20
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
30
0
0
10
0
0
0
10
10
0
% E
% Phe:
0
0
0
10
10
0
0
10
0
0
0
0
0
30
10
% F
% Gly:
30
10
30
40
30
10
10
0
10
10
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% K
% Leu:
10
0
0
0
0
10
20
10
10
0
0
10
0
10
0
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
0
30
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
20
10
0
0
10
% N
% Pro:
0
20
10
0
20
20
10
30
0
10
0
10
10
0
10
% P
% Gln:
10
0
30
0
0
20
0
10
10
10
0
10
0
0
0
% Q
% Arg:
0
0
10
0
10
0
0
10
30
10
0
0
0
0
0
% R
% Ser:
30
40
0
20
30
10
20
20
10
0
50
40
10
30
20
% S
% Thr:
0
0
10
0
0
0
10
0
0
10
0
0
0
10
0
% T
% Val:
10
0
0
10
0
0
0
0
0
20
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _